Journal Articles - Natural Science - 2020

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http://repository.vlu.edu.vn:443/handle/123456789/113

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Parmosidone K, A New Meta depsidone from The Lichen Parmotrema Tsavoense

( 2020)
Thi-Hoai-Thu Nguyen
;
Thi-My-Nhung Nguyen
;
Thanh-Trung Nguyen
;
Huu-Hung Nguyen
;
Ngoc-Hong Nguyen
;
Dinh-Tri Mai
;
Bui-Linh-Chi Huynh
;
Cong-Luan Tran
;
Thuc-Huy Duong

Further phytochemical investigation on P. tsavoense led to one new meta-depsidone, parmosidone K together with one known compound, barbatic acid. Their structures were determined by 1D and 2D NMR analysis, high resolution mass spectroscopy, and comparison their NMR data with those reported in literatures. Parmosidone K was evaluated for α-glucosidase inhibition and revealed the powerful activity with IC50 value of 3.12 µM.
Two new phenolic compounds from the Vietnamese lichen Parmotrema tinctorum

( 2020)
Van-Muoi Bui
;
Thuc-Huy Duong
;
Thi-Anh-Minh Nguyen
;
Thi-Ngoc-Van Nguyen
;
Ngoc-Hong Nguyen
;
Huu-Hung Nguyen
;
Warinthorn Chavasiri
;
Kim-Phi-Phung Nguyen
;
Bui-Linh-Chi Huynh

Chemical investigation of the lichen Parmotrema tinctorum (Nyl.) Hale led to the isolation of two new phenolic compounds, 2-ethylhexyl orsellinate (1) and tinctorinone (2). The structures were determined by analysis of their MS and NMR data as well as by comparison with literature data. The 2-ethylhexyl ester group of 2-ethylhexyl orsellinate is uncommon among lichen metabolites. Tinctorinone revealed strong inhibition towards α-glucosidase.