Small and medium sized enterprises (abbreviated hereinafter as SMEs) play important roles and create economic growth and strategic management is considered an important element for business development. This study is conducted to explore the practice and strategic management in SMEs in Dong Thap province and its findings are used as foundations to formulate the recommendations to SMEs for their enhancement and improvement of the practice of strategic management. With the purpose of being foundations for the study, secondary data is used by collecting from vast literature and previous researches. Later, the systematic and content analyses from the vast secondary data are used to reduce the bias. Furthermore, to reach the objectives of the study, the primary data is generated through online questionnaire/ surveys, semi-structured talks and interviews with SMEs’ owners and managers.