The internal control system of commercial banks has become increasingly meaningful in the stable and sustainable development of the national financial system over the past time. In order to evaluate of internal control systems in the practical application of Vietnamese commercial banks, the authors conducted empirical research with 382 experts of most commercial banks in Vietnam. The results show that the internal control system of commercial banks has certain effects but still some shortcomings in each component. Thereby, the authors proposed a number of policy suggestions to develop internal control system of Vietnamese commercial banks to ensure efficiency to meet regional and international integration trends.