Publication:
Parmosidone K, A New Meta depsidone from The Lichen Parmotrema Tsavoense
Parmosidone K, A New Meta depsidone from The Lichen Parmotrema Tsavoense
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Date
2020
Authors
Thi-Hoai-Thu Nguyen
Thi-My-Nhung Nguyen
Thanh-Trung Nguyen
Huu-Hung Nguyen
Ngoc-Hong Nguyen
Dinh-Tri Mai
Bui-Linh-Chi Huynh
Cong-Luan Tran
Thuc-Huy Duong
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Research Projects
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Abstract
Further phytochemical investigation on P. tsavoense led to one new meta-depsidone, parmosidone K together with one known compound, barbatic acid. Their structures were determined by 1D and 2D NMR analysis, high resolution mass spectroscopy, and comparison their NMR data with those reported in literatures. Parmosidone K was evaluated for α-glucosidase inhibition and revealed the powerful activity with IC50 value of 3.12 µM.
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Keywords
pamotrema,
pamotrema tsavoense,
depsidone,
parmosidone