Publication:
New diterpenoids from the stems of <i>Euphorbia antiquorum</i> growing in Vietnam
New diterpenoids from the stems of <i>Euphorbia antiquorum</i> growing in Vietnam
| datacite.subject.fos | oecd::Natural sciences | |
| dc.contributor.author | Thanh-Nha Tran | |
| dc.contributor.author | Jirapast Sichaem | |
| dc.contributor.author | Van-Kieu Nguyen | |
| dc.contributor.author | Huu-Hung Nguyen | |
| dc.contributor.author | Truong-Tam Cao | |
| dc.contributor.author | Thi-Phuong Nguyen | |
| dc.contributor.author | Van-Giau Vo | |
| dc.contributor.author | Nakorn Niamnont | |
| dc.contributor.author | Ngoc-Hong Nguyen | |
| dc.contributor.author | Thuc-Huy Duong | |
| dc.date.accessioned | 2022-11-03T08:57:52Z | |
| dc.date.available | 2022-11-03T08:57:52Z | |
| dc.date.issued | 2020 | |
| dc.description.abstract | Phytochemical analysis of Euphorbia antiquorum stem extracts afforded two new ent-atisane compounds, ent-3α-acetoxy-16β,17,18-trihydroxyatisane (1) and ent-3α,14,16β,17-tetrahydroxyatisane (2) together with three known compounds, 20-deoxy-16-hydroxyingenol (3), ent-14[S],16α,17- trihydroxyatisan-3-one (4), and agallochaol C (5). Their structures were elucidated by spectroscopic data analysis and comparison with published NMR data. Compounds 1-5 were evaluated for α-glucosidase inhibition and cytotoxicity. Compounds 1, 4, and 5 revealed significant inhibitory activity against α-glucosidase with the IC50 values of 119.9, 135.5, and 134.3 μM, respectively. None showed activity in cytotoxicity assay. | |
| dc.identifier.doi | 10.1080/14786419.2020.1789634 | |
| dc.identifier.uri | http://repository.vlu.edu.vn:443/handle/123456789/842 | |
| dc.language.iso | en_US | |
| dc.relation.ispartof | Natural Product Research | |
| dc.relation.issn | 1478-6419 | |
| dc.relation.issn | 1478-6427 | |
| dc.subject | "Euphorbiaceae | |
| dc.subject | Euphorbia antiquorum L. | |
| dc.subject | ent-atisane diterpenoid | |
| dc.subject | α-glucosidase inhibition" | |
| dc.title | New diterpenoids from the stems of <i>Euphorbia antiquorum</i> growing in Vietnam | |
| dc.type | journal-article | |
| dspace.entity.type | Publication | |
| oaire.citation.issue | 2 | |
| oaire.citation.volume | 36 |