Publication:
A novel gold nanoparticle-based colorimetric assay for highly sensitive detection of ascorbic acid

datacite.subject.fos oecd::Engineering and technology
dc.contributor.author Thi Hong Anh Nguyen
dc.contributor.author Vu Tuyet Mai Nguyen
dc.contributor.author Van Thuan Le
dc.contributor.author Van-Dat Doan
dc.contributor.author Tan Phat Chau
dc.contributor.author Van Cuong Nguyen
dc.contributor.author Anh-Tien Nguyen
dc.contributor.author Yasser Vasseghian
dc.date.accessioned 2022-11-09T09:05:39Z
dc.date.available 2022-11-09T09:05:39Z
dc.date.issued 2022
dc.description.abstract In this study, a novel approach for colorimetric detection of ascorbic acid (AA) was proposed based on the peroxidase-like activity of gold nanoparticles, which were synthesized using Oldenlandia corymbosa leaves extract (OC-AuNPs). The OC-AuNPs synthesis was optimized at 0.5 mM Au3+, a reaction time of 20 min, and a temperature of 60 °C. The results showed that the biogenic OC-AuNPs presented as highly-efficient peroxidase mimics for catalyzing H2O2 to oxidize 3,3′,5,5′-tetramethylbenzidine forming a typical blue product with the characteristic absorption at 654 nm. The developed colorimetric method exhibited high sensitivity for AA with a detection limit of 0.26 μM in the linear range of 0 – 100 μM. The proposed assay can be serviced as a sensitive biosensor for the determination of AA in aqueous solutions due to its simple detection procedure, fast operation, and high sensitivity.
dc.identifier.doi 10.1016/j.matlet.2021.131307
dc.identifier.uri http://repository.vlu.edu.vn:443/handle/123456789/1089
dc.language.iso en_US
dc.relation.ispartof Materials Letters
dc.relation.issn 0167-577X
dc.subject Oldenlandia corymbosa
dc.subject AuNPs
dc.subject Colorimetric detection
dc.subject Ascorbic acid
dc.subject Peroxidase mimic
dc.title A novel gold nanoparticle-based colorimetric assay for highly sensitive detection of ascorbic acid
dc.type journal-article
dspace.entity.type Publication
oaire.citation.volume 309
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