Publication:
Two new cycloartanes from the leaves of Combretum quadrangulare growing in Vietnam and their biological activities
Two new cycloartanes from the leaves of Combretum quadrangulare growing in Vietnam and their biological activities
datacite.subject.fos | oecd::Natural sciences | |
dc.contributor.author | Huu-Hung Nguyen | |
dc.contributor.author | Thi-Phuong Nguyen | |
dc.contributor.author | Nguyen Tien Trung | |
dc.contributor.author | Cam-Tu D. Phan | |
dc.contributor.author | Thi-Bich-Ngoc Dao | |
dc.contributor.author | Dinh-Tri Mai | |
dc.contributor.author | Jirapast Sichaem | |
dc.contributor.author | Ngoc-Hong Nguyen | |
dc.contributor.author | Cong-Luan Tran | |
dc.contributor.author | Thuc-Huy Duong | |
dc.date.accessioned | 2022-10-14T03:54:11Z | |
dc.date.available | 2022-10-14T03:54:11Z | |
dc.date.issued | 2021 | |
dc.description.abstract | Two novel cycloartanes, combretanones G and H (1 and 2), were isolated from the leaves of Combretum quadrangulare. Their structures were elucidated by applying a set of spectroscopic methods, while their relative configurations were determined using DFT-NMR chemical shift calculations and subsequent assignment of DP4 probabilities. Compounds 1 and 2 are C-23/C-24 stereoisomers of the previously-reported euphonerin E. Both exhibited moderate cytotoxicity against three human cancer cell lines. Compound 2 was shown to be a potent antiparasitic. Our results confirm the traditional medicinal uses of Combretum quadrangulare in Vietnam. | |
dc.identifier.doi | 10.1016/j.arabjc.2021.103189 | |
dc.identifier.uri | http://repository.vlu.edu.vn:443/handle/123456789/265 | |
dc.language.iso | en_US | |
dc.relation.ispartof | Arabian Journal of Chemistry | |
dc.relation.issn | 1878-5352 | |
dc.subject | "Combretaceae | |
dc.subject | Combretum quadrangulare | |
dc.subject | Cycloartane | |
dc.subject | Combretanones G and H" | |
dc.title | Two new cycloartanes from the leaves of Combretum quadrangulare growing in Vietnam and their biological activities | |
dc.type | journal-article | |
dspace.entity.type | Publication | |
oaire.citation.issue | 7 | |
oaire.citation.volume | 14 |
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