Publication:
Two new cycloartanes from the leaves of Combretum quadrangulare growing in Vietnam and their biological activities

datacite.subject.fos oecd::Natural sciences
dc.contributor.author Huu-Hung Nguyen
dc.contributor.author Thi-Phuong Nguyen
dc.contributor.author Nguyen Tien Trung
dc.contributor.author Cam-Tu D. Phan
dc.contributor.author Thi-Bich-Ngoc Dao
dc.contributor.author Dinh-Tri Mai
dc.contributor.author Jirapast Sichaem
dc.contributor.author Ngoc-Hong Nguyen
dc.contributor.author Cong-Luan Tran
dc.contributor.author Thuc-Huy Duong
dc.date.accessioned 2022-10-14T03:54:11Z
dc.date.available 2022-10-14T03:54:11Z
dc.date.issued 2021
dc.description.abstract Two novel cycloartanes, combretanones G and H (1 and 2), were isolated from the leaves of Combretum quadrangulare. Their structures were elucidated by applying a set of spectroscopic methods, while their relative configurations were determined using DFT-NMR chemical shift calculations and subsequent assignment of DP4 probabilities. Compounds 1 and 2 are C-23/C-24 stereoisomers of the previously-reported euphonerin E. Both exhibited moderate cytotoxicity against three human cancer cell lines. Compound 2 was shown to be a potent antiparasitic. Our results confirm the traditional medicinal uses of Combretum quadrangulare in Vietnam.
dc.identifier.doi 10.1016/j.arabjc.2021.103189
dc.identifier.uri http://repository.vlu.edu.vn:443/handle/123456789/265
dc.language.iso en_US
dc.relation.ispartof Arabian Journal of Chemistry
dc.relation.issn 1878-5352
dc.subject "Combretaceae
dc.subject Combretum quadrangulare
dc.subject Cycloartane
dc.subject Combretanones G and H"
dc.title Two new cycloartanes from the leaves of Combretum quadrangulare growing in Vietnam and their biological activities
dc.type journal-article
dspace.entity.type Publication
oaire.citation.issue 7
oaire.citation.volume 14
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