Publication:
Health risk assessment of volatile organic compounds at daycare facilities

datacite.subject.fos oecd::Natural sciences
dc.contributor.author Mohamed Bayati
dc.contributor.author Danh C. Vu
dc.contributor.author Phuc H. Vo
dc.contributor.author Elizabeth Rogers
dc.contributor.author Jihyun Park
dc.contributor.author Thi L. Ho
dc.contributor.author Alexandra N. Davis
dc.contributor.author Zehra Gulseven
dc.contributor.author Gustavo Carlo
dc.contributor.author Francisco Palermo
dc.contributor.author Jane A. McElroy
dc.contributor.author Susan C. Nagel
dc.contributor.author Chung‐Ho Lin
dc.date.accessioned 2022-11-09T10:25:17Z
dc.date.available 2022-11-09T10:25:17Z
dc.date.issued 2021
dc.description.abstract Children are particularly vulnerable to many classes of the volatile organic compounds (VOCs) detected in indoor environments. The negative health impacts associated with chronic and acute exposures of the VOCs might lead to health issues such as genetic damage, cancer, and disorder of nervous systems. In this study, 40 VOCs including aldehydes and ketones, aliphatic hydrocarbons, esters, aromatic hydrocarbons, cyclic terpenes, alcohols, and glycol ethers were identified and qualified in different locations at the University of Missouri (MU) Child Development Laboratory (CDL) in Columbia, Missouri. Our results suggested that the concentrations of the VOCs varied significantly among classrooms, hallways, and playground. The VOCs emitted from personal care and cleaning products had the highest indoor levels (2-ethylhexanol-1, 3-carene, homomenthyl salicylate with mean concentration of 5.15 µg/m3, 1.57 µg/m3, and 1.47 µg/m3, respectively). A cancer risk assessment was conducted, and none of the 95th percentile dose estimates exceeded the age-specific no significant risk levels (NSRL) in all classrooms. Dimensionless toxicity index scores were calculated for all VOCs using a novel web-based framework called Toxicological Prioritization Index (ToxPi), which integrates multiple sources of toxicity data. According to the method, homomenthyl salicylate, benzothiazole, 2-ethylhexyl salicylate, hexadecane, and tridecane exhibited diverse toxicity profiles and ranked as the five most toxic indoor VOCs. The findings of this study provide critical information for policy makers and early education professionals to mitigate the potentially negative health impacts of indoor VOCs in the childcare facilities.
dc.identifier.doi 10.1111/ina.12801
dc.identifier.uri http://repository.vlu.edu.vn:443/handle/123456789/1127
dc.language.iso en_US
dc.relation.ispartof Indoor Air
dc.relation.issn 0905-6947
dc.relation.issn 1600-0668
dc.title Health risk assessment of volatile organic compounds at daycare facilities
dc.type journal-article
dspace.entity.type Publication
oaire.citation.issue 4
oaire.citation.volume 31
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