Huu-Hung Nguyen
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Preferred name
Huu-Hung Nguyen
Official Name
Huu-Hung Nguyen
Translated Name
Huu-Hung Nguyen
Alternative Name
Huu-Hung Nguyen
Researcher ID
GYJ-6241-2022

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  • Publication
    A study on the species composition of Toxocara spp. in infected home cats in Ho Chi Minh City
    ( 2021)
    Thi-Phuong Nguyen
    ;
    Huu-Hung Nguyen
    Toxocariasis is defined as a zoonotic disease caused by species of Toxocara genus, including Toxocara canis and Toxocara cati, which are potentially infectious to human. Toxocara malaysiensis, a roundworm in cat with similar morphology as Toxocara cati, was initially identified in Malaysia and as a common ascaridoid of cats in Hanoi, Vietnam. This study was conducted to investigate the species composition of Toxocara spp. in infected home cats in Ho Chi Minh City by morphological, and moculecular biology method, reconstruct the phylogenetic tree based on atp6 gene using MEGA 6.0 sofware. Toxocara spp. were identified including 4 individuals of T. cati species and 1 individual of T. malaysiensis species. Genetic distance between T. malaysiensis in this study and one from China was 0%. This study indicated the detection of Toxocara malaysiensis for the first time in Ho Chi Minh City.
  • Publication
    Analysis of pathogenic characteristics induced by Toxocara cati in experimental mouse model
    ( 2021)
    Thi-Tuyet-Trinh Thai
    ;
    Huu-Hung Nguyen
    Toxocara cati is a kind of round worm which parasitize in Felidea. Their larvae can infect human and induce toxocariasis. In human body, the larvae uncontrollably migrate and induce multi-organ damages. However, characteristics of toxocariasis in human are not fully understood. In this study, mice were used as a model of toxocariasis produced by intraperitoneal infection of T. cati larvae. The pathogenic characteristics were assessed by histopathology and the recovery of these worms from the animal organs after infection. Our results showed that the larvae induced remarkable damages in the liver and lungs and a countable number of larvae was found in the brain after 4 weeks of infection. The data indicates a high risk that the worms can make in human and requires further investigations.